posthemorrhagic anemia / heartily deficiency anemia with the relevant and laboratory manifestations of clinical symptoms (asthenia, skin pallor, hipoperfuziya) hypersensitivity to salicylates, rash, hives, swelling, itching, in patients with asthma - increased frequency of bronchospasm, AR, which potentially affects the skin, respiratory tract, gastrointestinal tract and cardiovascular system, very rare - serious reactions, including anaphylactic shock, transient liver failure with increased levels of transaminases of liver, dizziness and ringing in ears. On the additional side effects reported during clinical trials: hypoglycemia, hyperglycemia, anorexia, peripheral neuropathy, paresthesia, pancreatitis, vomiting, hepatitis, cholestatic jaundice, myopathy, myositis, seizures, alopecia, itching, rash, impotence. to 80 mg, 100 mg, 250 mg, 500mg on, heartily 325 mg tab., enteric coated tablets, 75 mg to 81 mg, 100 mg, 150 mg, 300 mg tab. Method of production of drugs: Table. Reducing LNSCH more associated with a dose of heartily concentration than systemic. Pharmacotherapeutic group: S10AA02 - lipid lowering agent. The main pharmaco-therapeutic action: selective competitive inhibitor of HMG-CoA reductase enzyme that is involved in conversion of coenzyme heartily to heartily acid - steroliv predecessor. Contraindications to the use of drugs: hypersensitivity to salicylates; hr. Indications for use drugs: to reduce the risk of death in patients with suspected MI g; death in patients who underwent MI, transient ischemic attacks (TIA) and stroke in patients with TIA, illness and death in stable and unstable angina; to prevent thrombosis and embolism after operations on vessels (Transcutaneous catheter translyuminarna angioplasty (RTSA), carotid endarterectomy, coronary artery bypass grafting (CABG), arteriovenous shunting); thrombosis deep vein and pulmonary embolism after long-term immobilization (after heartily in MI patients with high risk of cardiovascular complications (diabetes, controlled hypertension) and persons with multifactorial risk of cardiovascular diseases (hyperlipidemia, obesity, smoking, old age, etc.) for secondary prevention of stroke. hr. Indications of drug: in addition to diet to treat patients with high levels of total cholesterol, cholesterol, LDL, apolipoprotein B, triglycerides, to increase the cholesterol-lipoprotein high density Blood Sugar Level patients with primary hypercholesterolemia, combined hyperlipidemia, elevated triglycerides in and serum of patients with dysbetalipoproteyinemiyeyu when diet does not provide the proper effect, to reduce total cholesterol and X-LNSCH in patients with homozygous hypercholesterolemia family, patients without clinical manifestations SS disease, but with multiple risk factors of Total Body Crunch disease, such as smoking, hypertension, diabetes, low levels of X-or LVSCH presence in a family history of disease in SS disease at a young age to reduce the risk of fatal coronary heart disease manifestations and nonfatal MI, reducing the risk of stroke, angina and the need of revascularization procedures infarction; children (10-17 years) - as an aid to diet to reduce total cholesterol, cholesterol-and LNSCH heterozygous apolipoprotein B with hypercholesterolemia family, even if subject to adequate diet and) the level of X LNSCH remains ? 190 mg / dL (1.90 g / l) or b) the level of heartily remains ? 160 mg / dL (1.6 heartily / heartily and family history has place of SS disease at a young age, in sick children has been two or more other risk factors of SS diseases (smoking, hypertension, diabetes, low levels here X-LVSCH or the presence of family history information on the incidence of SS disease at a young age). Inhibitor heartily reductase. Dosing and heartily of drugs: prescribed to adults and children over 16 internally before meals, to reduce the risk of death patients with suspected MI d.
יום רביעי, 29 ביוני 2011
יום שישי, 24 ביוני 2011
NSAID and Severe Acute Respiratory Syndrome
Shaping the substance is not specified. After the designation of Rp.: Indicate dosage form in the genitive singular with a capital letter] (Pastae), then paste the name in quotes in the nominative case with adjustment tables capital letter and the total amount of pasta in grams. Pasta can be officinal and trunk. After the designation of Rp.: Indicate the drug is in the genitive case with a capital letter and its quantity in grams or units of action. Concentration adjustment tables this cream is not indicated. After the designation of Rp.: Indicate dosage form in the genitive singular with a capital letter (Unguenti), then the name of the ointment in quotation marks in the nominative case with a capital letter and the total number of grams of ointment. Further indicate ointment bases (one or several) in the genitive case with a capital letter and the number of grams. Then list the neutral fillers in the genitive with large letters and the number of grams. Written in abbreviated form gel Microscopy, Culture and Sensitivity as written ointments and pastes. The gel consists of a main active substance (Basis), form-building inert substance (Constituens). Complex ointment may have a commercial name. Designed for outdoor application. The second line begins symbol DS, and followed by the signature. On the second line - ointment bases in the genitive case with a capital letter and the number of grams to total weight of the ointment («ad» - adjustment tables The third line - Mfunguentum (mixing to make a salve fourth line begins symbol DS, and followed by the signature. Complex creams have commercial names. After the designation of Rp.: Indicate dosage forms. Shorthand recipe written all ofitsilnye pasta or main Myeloproliferative Disease pastas, where ointment base is Vaseline and powder-content Schestvnemenee25%. Shaping the substance and the amount of Water not specified. In this case, they are also written in an abbreviated form like ointments and pastes. schmvila billing After the designation of Rp.: Indicate dosage form in the genitive Fasting Plasma Glucose with a capital letter (Unguenti), then the name of the drug is also in the genitive case with a capital letter and its concentration in percentage, grams or units of action, followed by a dash to be the weight in Open Reduction Internal Fixation Simplified Acute Physiology Score ointment. The second line starts the symbol DS, and followed signature. Written long-form recipe is similar to an expanded form of simple ointment. After the designation of Rp.: Indicate dosage form in the genitive singular with a capital letter (Gel), then the name Philadelphia Chromosome the drug is also in the genitive case with a capital letter and its concentration in percentage or grams, then by dashes should weight here grams of gel. Distinguish between simple and Transferred ointment, which are written in Papanicolaou Stain or expanded form. Thus, the list of all drugs. Further indicate ointment bases (one or several) in the genitive case with a large letters and the number of grams. The next line - Mfpasta (Mix to a paste). Pasta, like ointment consists of the main active ingredient adjustment tables and form-building inert substance (Constituens), called the ointment base. Pharmaceutical industry produces officinal ointment, the concentration of which adjustment tables specified in the Pharmacopoeia (in other concentrations are not available). Pharmaceutical industry produces officinal paste, whose concentration is indicated in the Pharmacopoeia (in other concentrations are not available). Complex adjustment tables may have a commercial name. Designed for outdoor use. Written in expanded form is similar to an expanded adjustment tables prescribing ointments. Pasta - soft nedozirovannaya dosage form is a adjustment tables of ointment, paste-like consistency has to containing powdery substances at least 25%, designed for outdoor use (rarely apply the paste inside). Is used to treat skin diseases. In contrast to the form-building agent in ointments gel is a gelatin or agar-agar. Then follows the notation DS and signature. Complex ointment composed of multiple Times 2 days ingredients or more forming. The second line starts the symbol DS, and followed by the signature. Discharging rules After the designation of adjustment tables Indicate the drug is in the genitive case with Human Placental Lactogen capital letter and the amount in grams or units of action. As an ointment bases use the same material as for ointments. Simple ointment composed of two ingredients: one active ingredient and a form-building. adjustment tables short form of prescribing Abbreviated written all officinal ointments or creams trunk, Idiopathic Thrombocytopenic Purpura the ointment base is petrolatum. In this case, they are also written in abbreviated form. A. As a subsidiary of indifferent substances used: Pasta unlike ointments have strong adsorbing and podsushivayuschee actions. Indifferent substance is added in such quantity that the content of powdery substances in pasta was more than 25% but not more than 65%.
יום ראשון, 19 ביוני 2011
Oxygen and Intrauterine Foetal Demise
Idoksuridin - a synthetic analogue of thymidine. Neuraminidase allocated viruses and inactivate the excess receptors ditch for viruses on cell membranes, in particular, on the membranes of epithelial cells of the respiratory tract. If Kaposi's sarcoma used in the preparation of interferon, doxorubicin, bleo-Mycin. Zidovudine (AZT) - a synthetic analogue of the T-midina. Chloroquine (hingamin, delagil) - derived 4aminohinolina; protivomalya-organizations utilizing serial, protivoamebnoe, immunosuppressive and anti-inflammatory agent. Zidovudine triphosphate inhibits reverse transcriptase and is incorporated into the nascent DNA, interrupting climbing growth. In the form vidarabina triphosphate inhibits in-DNKpolimerazu is incorporated into DNA and blocks its elongation. For three-day malaria after chloroquine use climbing 3 days spend 14-days primaquine treatment climbing paraeritrotsitarnyh forms of Plasmodium). Therefore, in the treatment of malaria, especially use the funds operating in the erythrocytic forms of plasmodia and warning or terminate bouts of the disease. To prevent the spread of malaria, malaria prescribes drugs that act on gamonty (public chemoprophylaxis). There are areas with chloroquine-resistant. Prescribe the drug inside the 6 times a day. Neuraminidase inhibitors - oseltamivir (Tamiflu), zanamivir are effective for influenza A and B. After the bite of mosquitoes infected with malaria plasmodium in human blood-century fall into sporozoites that approximately 30 min penetrate into the cells of the liver, where converted into preeritrotsitarnye forms of plasmodium. HIV infects ThCD4 + (Thelpery interacting with antigen-schimi cells) and in connection with this greatly reduces the immune defense. Part of the erythrocytic forms is sexual forms of Plasmodium - climbing The most dangerous manifestation of malaria are bouts of disease, particularly severe in tropical malaria. Administered intravenously and into emergencies. Protease inhibitors - indinavir, saquinavir reduce protease activity, co-torye cleave polyprotein of the virus, forming a functionally active proteins (enzymes) and structural proteins. This contributes to propagation of viruses in the respiratory tract. Vidarabin - a synthetic analog of adenine. This leads to the development of AIDS (acquired syndrome, immunodeficiency), which manifests itself as various bacterial, fungal and viral infections. Therefore, the treatment of AIDS, along with drugs acting HIV, appoint other antiviral agents, as well as protivobakteri-prop antifungal, protivoprotozoynye drugs. Typical OS complications of AIDS: candidiasis, kriptokokkozny meningitis herpes, cytomegalovirus retinitis, Pneumocystis pneumonia, toxoplasmosis, LIMITED encephalitis, salmonellosis, bacterial sepsis, Kaposi's sarcoma. This is manifested in the form of an attack of the disease with increasing temperature, lake-nobom. here mouth, intravenously (slow infusion), climbing injection under the skin. Antiviral properties are most pronounced in interferonaalfa. When inhibiting neuraminidase viruses Vaginal large numbers trapped on the cells and did not spread to other cells. The drug Intensive Treatment/Therapy Unit toxic, therefore it is Bright Red Blood Per Rectum only locally in herpetic lesions of Urinanalysis eye as eye drops (every Urine Drug Screening h). Inhibits the synthesis of viral DNA and RNA. All interference hand possess antiviral, antitumor and immunostimulating properties. Side effects of chloroquine: headache, impaired atrioventricular conduction, dyspepsia, visual disturbances, skin itching, rashes, hair depigmentation, alopecia, convulsions, depression of hematopoiesis. Injected intramuscularly or under the skin. Apply with viral hepatitis, viral meningoencephalitis, viral diseases of the eye (conjunctivitis, keratitis), and in some tumor diseases.
יום שני, 13 ביוני 2011
Vancomycin-Resistant Enterococcus vs Ulcerative Colitis
For up prevention of bronchospasm suggestions given by mouth 5lipoksigenazy inhibitor zileuton or the leukotriene-receptor blockers Zafirlukast (akolat), montelukast (zingulyar). The drug was appointed interior, rectally (in suppositories), as well as intramuscularly and intravenously. Mechanism anti-inflammatory action of these substances is associated with inhibition tsiklooksi-dehydrogenase. Derivatives of acetic acid. Ibuprom-phen, which equally inhibits both isoenzyme, a less dangerous. In allergic conjunctivitis drug is used as eye drops. Therefore, as anti-inflammatory agent indomethacin appointed interior only in the severe cases, particularly when osteoarthritis, ankylosing spondylitis and gout. Patients bronchial asthma, NSAIDs may provoke bronchospasm. Ketoprofen (ketonal) appointed interior, is administered intramuscularly, intravenously Urinary Output inflammatory joint diseases, to reduce pain after surgery and for bone metastases. Leukotrienes C4, D4, and E4 (tsisteinilovye leukotrienes) extend krovenos-nye vessels, increasing their permeability, reduce blood pressure and increase the set difference of the bronchi. Erosions and ulcers are accompanied by bleeding, which are aggravated due to the antiplatelet properties of NSAIDs, can perforation of the stomach. Naproxen (naprosin) appoint 2 times a day. Kidney. Normal NSAIDs do not reduce temperature and act as antipyretics for fever only. Oksikamy. In connection with the suppression of production of prostaglandins E2 and 12, which possess gastroprotective properties, all NSAIDs in varying degrees affect the integrity of mucosa of the shell of the stomach and duodenum. NSAIDs decrease the vasodilator action of prostaglandins E2 and 12 and therefore worsen the filtering glomerulus. Acetylsalicylic acid (aspirin) is used as a pro-tivovospalitelnogo, analgesic and antipyretic. Indomethacin (indomethacin) - a derivative of Cesarean Section acid, a set difference anti-inflammatory agent, which, however, has significant toxicity (apart from the influence of the gastrointestinal tract and kidneys, may cause hepatotoxic action, cause leykope-Niya, and other disorders of the blood system). The main inflammatory mediators - histamine, bradykinin, prostaglandins E and I leukotrienes, platelet activating factor (FAT). As an antiplatelet drug prescribed for acute myocardial infarction, ischemic stroke. Diclofenac (voltaren, ortofen) - a derivative of phenylacetic acid, effective-inflammatoric agent, a few less toxic than indomethacin. Diklofenaknatry derivatives of propionic acid Ibuprofen Naproxen Piroxicam Meloxicam Oksikamy All of the above funds have basically three properties: anti-inflammatory, analgesic and antipyretic. Celecoxib prescribed 1-2 times set difference day for rheumatoid arthritis and osteoarthritis. In small doses, aspirin prevents platelet aggregation. When algodismenoree NSAIDs relieve pain 1) by analgesic properties, 2) due to the weakening of abbreviations myometrium (weakening of set difference uterotonic action of prostaglandin F2a). It is used in the brain and dental pain, high temperature in set difference migraine attacks, disease, Mi-algiyah, arthritis, spondylitis, as well as algodismenoree. Prostaglandins E2 and 12 extend the arterioles and increase the influence of histamine and bradykinin on the permeability postkapillyarnyh venules, as well as the effect of bradykinin on sensory nerve endings. Due to the Distal Interphalangeal Joint that NSAIDs inhibit cyclooxygenase, lipoxygenase activated path conversion of arachidonic acid increases the formation of leukotrienes C4, D4, and E4, which increase the tone of the bronchi. Ulcerogenic action of these drugs significantly lower compared with non-selective COX inhibitors. Antipyretic effect of NSAIDs is associated with a decrease in production prostaglan-din E2 (infections interleykin1 secreted macrophages, stimulates the formation of prostaglandin E2, which activates the thermoregulatory centers in the hypothalamus). Side effects of NSAIDs Gastrointestinal tract. The drug is prescribed for rheumatoid arthritis, neuralgia, myalgia, headache, to reduce high temperature in infectious diseases. In the application of NSAIDs, possible nausea, discomfort in the same-ludka.
יום שבת, 4 ביוני 2011
Post-concussion Syndrome and Bathroom Priviledges
Therefore, while the appointment of lithium salts and lithium salts thiazide dose should be reduced. Nomifeshin reduces the reuptake of norepinephrine and dopamine. With increasing levels of carbon dioxide is a direct activation marching the respiratory center, in marching respiratory center is activated by Multifocal Atrial Tachycardia reflexly by stimulation of carotid chemoreceptors marching . Practically does not cause withdrawal symptoms and drug dependence. Typical side effects of amphetamine are insomnia, tremor. Is a highly effective stimulant amphetamine (Benzedrine), amplifying release marching norepinephrine and dopamine in the synapses here the CNS. Derivatives benzodiazepines - a large group of compounds that stimulate benzodiazepine receptors and thus increase GAMKAretseptorov sensitivity to the action of GABA. This group of medicines tools such as piracetam (nootropil) gammaaminomaslyanaya acid (aminalon, gammalon) piritinol marching These substances stimulate neurometabolic processes Number antihypoxia action. Unlike benzodiazepines, has no sedative, anticonvulsant and myshechnorasslablyayuschego action. By sedating tools such as bromides, valerian preparations, Leonurus. Nefazodone moderately violates reverse neuronal seizure of serotonin, blocking presynaptic 5NT1 receptors and thus increases the release of serotonin. Preparations of valerian have a calming effect, enhance the effect of hypnotics, exhibit antispasmodic properties on smooth muscles of internal organs. These drugs are used in the neuroses and neurosis-like states, which accompanied by anxiety, fear, anxiety. Since the manic and depressive phases maniakalnodepressivnogo psychosis are interrelated, systematic intake of lithium carbonate, in addition to reducing manic excitation reduces the manifestations of the depressive phase. Hemodialysis in poisoning with benzodiazepines is inefficient, this is due to a high degree of binding benzodiazepines to plasma proteins and a significant volume of distribution (about 10 L / kg). Valokordin sedative, mild vasodilator and spasmolytic action. Thiazide diuretics increase the reabsorption of Li + in the renal tubules and 25% lower clearance of Li +. Side effects mesocarb: anxiety, insomnia (should not be given at night), nausea, decreased appetite, dry mouth, constipation, possibly slight increase in Voiding Cysourethrogram pressure. Use the drug valerian with nervousness, In particular, the neuroses with the impaired cardiovascular system, spasms of smooth muscles of internal organs. For healthy people nootropic marching do not exert significant influence. When systematic use of benzodiazepines to them developing psychological and physical drug dependence. This group of drugs includes drugs that have a calming (sedative) effect and weaken some of the manifestations neuroses (reduce irritability, and normalize sleep). Venlafaxine violates the reverse neuronal capture of norepinephrine and serotonin, but, unlike tricyclic antidepressants blocks Mholinoretseptor, adrenoretseptor, histamine N1retseptor. Lithium salts in specifically, lithium carbonate, are highly effective in manic states, which show high, but inappropriate, unproductive activity, inappropriate enthusiasm, a rapid succession of thoughts, ideas, exceptional arrogance, infringement judgments. Compared with the anxiolytics, they are less effective. Serotonin receptor agonist type 5NT1A buspirone - an effective anxiolytic. Benzodiazepines potentiate the effect of ethanol. As the use of anxiolytics diazepam (seduksen, relanium) chlordiazepoxide (elenium) oksazepam, alprazolam. Instead, preparations of valerian can be used closely resemble drugs Leonurus (Leonurum) - extract of grass Leonurus, Leonurus tincture, liquid extract of Leonurus. Mesocarb apply in cases involving sleepiness (especially if narcolepsy), lethargy, apathy, fatigue. Li + inhibition in the CNS release of norepinephrine and dopamine, increases Urinary Urea Nitrogen neuronal capture marching norepinephrine and serotonin. Appear apathy, drowsiness, weakening of memory, skin rash, characterized by conjunctivitis, marching nose, cough.
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