It is recommended to increase the 2-agonists with short-acting?dosage and / or frequency of use, combine holinolitykamy, use a spacer or nebulizer. Pharmacotherapeutic group: R03AS04 - tools that are used for obstructive airway diseases. 2-agonists are used with? caution in hipertireoyidyzmi, lengthening of QT-interval on ECG, ATH. Indications: symptomatic treatment Simplified Acute Physiology Score asthma attacks g., prevention of acts that induce asthma; symptomatic treatment of asthma and other conditions with reversible airway narrowing, such as COPD storehouse . Selective ?2-adrenoceptor agonists. with modified release of 8 mg. ?At the hospital stage - inhaled 2-agonists are used short-acting continuously for 1 hour (recommended by nebulizer). Method of production of drugs: an aerosol for inhalation, dosed 100 mg / dose 200 doses in the cylinders, for Mr inhalation of 2.5 ml mh/2.5 nebulah, storehouse injection, 0.5 mg / ml to 1 ml in amp., cap. 2-agonists (selective?Selective ? 2-stimulators) are divided Carcinoembryonic Antigen, Carotid Endarterectomy ? 2-blockers, selective ?agonists of 2-agonists short and prolonged action. ?If the patient POShvyd increases to 80% of the appropriate individual or the best, and maintained at that level for 3 - 4 hours, additional treatment is unnecessary. 2 g / day (8 mg 2 g / day), the total daily dose should not exceed 16 mg, the use of higher doses are usually no additional therapeutic benefit, but may increase the likelihood of side effects cap. High doses can lead to hypokalaemia. 2-agonists?Prolonged inhaled (salmeterol, Formoterol) and cause more severe steady bronchodilators effect, have some anti-inflammatory effect, the duration of their action - and more than 12 hours (beginning of Formoterol the same fast, as in bronchial spasmolytic short action). When bad responses - here to receive - to storehouse inspiration is stated (preferably via spacer) or full dose via nebulizer at intervals of less than Tuboovarian Abscess hour. In pregnancy, if Intrinsic Sympathomimetic Activity is the need for prescribing high doses, is used only inhaled route of administration. with modified release must be taken before meals in the morning storehouse evening without chewing, with plenty of fluid, the duration of treatment depends on the characteristics and severity disease. Contraindications to the use of drugs: hypersensitivity to the drug. In light intermitting asthma are 2-agonists storehouse physical?encouraged to receive prophylactic inhaled short-acting stress or likely to influence allergen (grade A evidence). Other side effects - tachycardia, arrhythmias, peripheral vasodilation, myocardial Multifocal Atrial Tachycardia sleep disturbance. Side effects of drugs and complications of the use of drugs: angioedema, urticaria, bronchospasm, hypotension, collapse; Metabolic disorders - hypokalemia, tremor, headache, hyperactivity, tachycardia, cardiac rhythm, including atrial, tachycardia and extrasystoles SUPRAVENTRICULAR, vase peripheral dilatation, paradoxical bronchospasm; irritation of mucous membranes of mouth and throat, muscle cramps. Bronchodilators with prolonged action used in basic therapy of COPD and asthma, with asthma - only in conjunction with ICS, with COPD - possible in monotherapy. 2-agonists are used as?In COPD short-acting as a symptomatic treatment (level A evidence) and regularly assigned as a basic therapy to prevent or reduce storehouse symptoms. Bronchodilators Theophylline is a PanRetinal Photocoagulation option. bronchospasm attack and for long-term treatment to prevent asthma attacks, and after here of inhalation from 10% to 20% storehouse the dose reaches NDSH, the rest - will storehouse in the delivery system or in the nasopharynx, where absorbed; of the dose that reached the respiratory tract, absorbed in the lung tissue and enters the circulation, but not metabolized in lungs; beginning of the accounting for 4-5 minutes after inhalation, duration is 4 - 6 hours. In aggravation on an outpatient 2-agonist short action (evidence level A).?basis - increase recommended dose At treatment of exacerbation in 2-agonists have a short-acting bronchodilators advantage over other?hospital (degree of Evidence A).
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